egr hell!!!!!
It could. You need to work it from the point of diagnosing a miss. What's causing it, air fuel spark or timing. Try to determine which cylinder is missing. I think a vacuum test would be helpful.
OK the knock sensor is a piezoelectric sensor. That means it makes voltage when it vibrates. The common way to test the system is to let the truck idle and hit the block with a wrench or hammer ( metal ) and see if the sensor retards the timing. I believe there is only one wire. It goes back to the pcm and looks for voltage from the knock sensor.
You really needs to use a timing light or a tach to tell the change. It will only be a little bit of timing. But if there is no change then the circuit is bad. You can test the sensor with volt meter. Measure for voltage when you hit the block. An analog volt meter might be easier to read for this of you have one. Next you can test the wire for continuity. It may also be a good idea to have the ecu tested at this point.

