I stay pretty close to these settings on 89 Octane:
Level 2 custom settings
Gear Ratio = whats in the truck, confirm it with your axle code
Tire Size = enter correct diameter
Idle Speed = I never adjust this
WOT Shifting = 1-2 and 2-3 @ 5000 and 3-4 @ 4600 rpm
Std. Shifting = leave alone
Shift Firmness = 1-2 is +2, 2-3 is +6 and 3-4 +8
Rev Limiter = 5500 rpm
Speed Limiter = what ever you are comfortable with, I do 120 mph
Timing Adjustment = +.25 or +.50 (if you do +.50, make sure your engine doesnt ping)
WOT Fuel = no need to go over +1.50

 

Thanks! Where do I get my axle code? On the door sticker?

 

Yes, follow this guide:

http://www.fordf150.net/howto/decode.php

 

Most importantly have fun with it