I have 2 keys from ford and had a copy of one made at lowes it opens and u locks doors and goes in ignition and turns over all the way to run but will not start truck

 

Your manual (available online also) will describe this process.

Here are general instructions, some model years may be slightly different:

1. Insert an existing working key into the ignition cylinder.

2. Turn the ignition cylinder to ON (RUN) and back to OFF.

3. Remove the existing working key and, within five seconds, insert a second working
key and turn it to ON (RUN) then back OFF.

4. Remove second working key and insert the new key before ten seconds have
elapsed and turn it to ON (RUN). Leave it on for one second and turn back to OFF.

5. The security light will light up for three seconds to indicate that the new
key has been successfully programmed.

 

Here is the key they cut at lowes it works in position1,2,3 but will not start the truck