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it should work, just make sure that it was set back to stock before it's taken outta the other truck, cause from what i understand if you don't it wont work.
Bought a used Edge off of here and it was used on a 4.6 and works fine in my 5.4... We had the same questions and found out it is not a problem at all...
Oh yeah... been running mine for about 2 weeks without and you can definitely tell the difference... Run it in level 2 for a month and then take it off, you will have a new respect for it...