Mustangs and F-150's are nothing alike. There are canned tunes out there via hypertech, superchips, and bullydog I think but If you want custom it will be done via the SCT X3 *Ithink* Check out PHP, Troyer, and VMP.
I know some have had them dyoned, but for me it was better driveability. The drive by wire from factory is just so lazy and the tunes really help. I def. noticed a difference but didn't have 1000 miles on mine before it had a tune.