Gotta issue with my 2010 F150 Crewcab, one morning on my way to work my windows wouldn't roll down, turned truck off and back on it worked fine. Later that night I went to get something and the radio was playing with no keys in ignition. Replaced accessory relay but that didn't work, battery and alternator are good and so are the fuses

 

Check the wires. Possibly call these guys:

 

APIM perhaps? or audio control module? Been down this road in the last month with both items and out $700.

 

Ouch

 

That's why you check the cheaper stuff, first.