My power locks suddenly unlocked (both doors) today while I was driving on the freeway. I was about 6 miles into my trip. Has this ever happened to anyone? My 2012 F150 just hit the 700 mile mark so I am still breaking it in. I am not overly concerned, just wondering if this will happen every so often.

 

Never happened to me (10,000 miles).
If you're sure you didn't bump the button, I'd take it to the dealer to check.