JohnyB

Could this be U-boat or my rear end has a Slight rubing sound

JohnyB

Just so you know it's a 2001 f-150 screw.

Marc D

Many places to look. Could be your rear U-Joint or the output shaft (pinion gear) on the rear end. Push the drive shaft up and down and look for lateral movement. Also check the driveshaft for dents or deep scratches. I might be out of round and need to be balanced. You may also need a 4 wheel alignment.