Truck can idle for hours on end and drive all day in every gear just fine, but when I'm cruising around 50mph in 5th gear I seem to lose power or voltage or something. I'll be driving and all of a sudden all my gauges die and throttle doesn't work and then everything is fine. Usually only lasts for a second or two, but this afternoon it lasted for about 5 seconds. No throttle response no gauge functions no check engine light no jolt or kick. Has anyone else experienced this?

 

Did you try pulling codes?

 

Did self test and no codes present other than 522- not in park or neutral, I have a standard.

 

Sounds almost like you're losing the main power feed from the battery - causing the ECU to cut out.

Start at the battery, checking and cleaning connections - a wiring schematic will help you trace the cabling from battery positive onwards - look for signs of internal corrosion in cables (greenish crud at connectors) or external damage. If all seems OK then perhaps there's an intermittent heat-related fault on the ECU itself.

Hopefully, someone else will come along to chime in with 2c worth...