The Crankshaft Position Sensor (or MIsfire sensor) sure can make a difference in how one runs! I had a bad one & like to have never figured it out!!
Code reader showed misfire on cylinder 6. & a P0118 (Engine Temp Control Sensor) Started with plugs, wires, dist cap & rotor. Then O2 sensor code (Bank 2 Sensor 2), replaced O2 sensor by cat converter. STill no better!!

STumbling, buck jumping in hi gear when mash on gas!!

Did everything but Put on smoke machine, but was acting like a vac leak, fuel press good, SOOOOO
I finally changed out Cam postion Sensor, WHOW! Then it threw a P0385, crankshaft sensor!!!
Changed it out & now truck runs fine!!
Now why did my Matco $150 code reader find that at first???
I spend $500 on parts!! SOmetimes "chasing codes" can be frustrating & a waste of time & money!!

 

I had same exact problem, ended up my fuel pump control module had a hole rusted in it and water was causing it to act up. Worth a shot to have it looked at seems to be hard to pinpoint this module but it causes these issues took a legit shop to take the time to work over truck with fine tooth comb to figure out. Dealership failed at it but local family owned mom pop shop did it and haven't had trouble since!

 

Moved out of how to section

You didn't say year?

 

had did mention Distributor cap and plug wires...must be old !! I really don't get it..because older motors don't have those sensors