First off, if the truck is idling/running fine, then leave it alone!
I would not recommend the use of a toothbrush, but instead would simply spray the backside and butterfly valve with throttle body cleaner; it's made for this function and will not remove any special coatings.
In watching several of the Saturday morning car shows, they have recommended this as a "tuneup" to help illiminate rough idle issues. And they too do not recommend any cleaner but those specifically designed for throttle bodies. And no scrubbing utensel!
Remove the throttle body first of course. It's an easy, 20 minute proceedure. I too would disconnect the battery; only because it forces the PCM to "re-learn" it's idle, which will get better on a dirty throttle body that's been cleaned. After re-installation, drive the truck for 20 minutes to a half hour.
Last edited by Bucko; 12-28-2011 at 10:02 AM.