Does the noise vary with engine speed or road speed?
Any changes when you apply the brakes?
2WD or 4WD?
First guesses based on the limited info would be a bearing failure in either the belt-driven accessories or front wheels, or brake pads that are worn way too far gone.
1989 F150 XLT standard-cab shortbed 4x4, 5.0L, AOD, 3.55 gears, manual hubs, 31x10.50 tires, 218K miles. Repainted Oct09. SOLD - Jan2015
2014 F150 XLT standard-cab shortbed 4x4, 5.0L, 6-speed auto, 3.55 gears, auto hubs, locking diff, trailer pkg, 5K miles.