Yeah mine's flipped out like that once before too. I was driving around and stopped and shut the truck off to fill up with gas. When I got back in it and started it up, as I was pulling away from the pump, I noticed the stereo display wasn't on, and it jumped to playing the radio instead of my USB drive...
I pulled into a parking spot there at the gas station and fiddled with it for a second or two and couldn't get it to respond. None of the steering wheel controls were working.
Then I shut the truck off, popped open the door to shut the stereo off, then started the truck back up, and all was well
Only happened to me once so far though. That's the bad thing about basically having a computer for a stereo... it's going to glitch every once in a while.