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got an 01 f450 7.3L it has been put through the ringer since day one.. just rolled 300k a week or two ago. Needs a/c compressor, door lock actuators and fuel filter atm. Besides that only problem we have had was a wheel bearing in the front crapping out on the highway.
Also 06 or 07 f650 with the cat motor and 16' flatbed has about 160k no problems as of yet.
my work 99 E350 7.3 has 287k and around 175k lost the power steering and just this January lost my master cylinder but other than that its a beast that runs like a rapped ape!
mine has a puny 120k without any big problems, jut brake calipers seizing and a busted track bar mount. My dads 02 f250 has 7.3 180k with a few alternators and strters replaced, thats it.